中心静脉导管腹腔置管联合新鲜血浆治疗肝硬化顽固性腹水对肝肾功能影响

目的探讨腹腔置管放腹水联合新鲜血浆治疗肝硬化顽固性腹水对肝肾功能影响。方法 98例肝硬化顽固性腹水患者被随机分为两组,治疗组48例,观察组50例。两组均行中心静脉导管腹腔置管放腹水,1次/d,1000mL/次,治疗组输注新鲜冰冻血浆200mL,1次/d;对照组输注白蛋白10g,1次/d。均于补液结束后应用速尿40mg静脉推注,疗程为10d。结果两组患者治疗后肝肾功能均有所改善,但是治疗组与对照组间比较、治疗组肝肾功能异常例数显著少于对照组（P〈0.05）具有统计学差异。结论中心静脉导管腹腔置管放腹水联合新鲜血浆治疗肝硬化顽固性腹水对肝肾功能改善具有良好作用。

Affect of Liver and Kidney Function of Peritoneal Catheter Central Venous Catheter Combined Fresh Plasma Treatment of Refractory Cirrhosis ascites

Objective Observe the affect of liver and kidney function of peritoneal catheter combined fresh plasma treatment of re- fractory cirrhosis ascites. Methods 98 cases of liver cirrhosis patients with refractory ascites, Were randomly divided into two groups,Treatment group 48 cases, observed group 50 cases＇ Both groups underwent central venous catheter peritoneal catheter paracentesis ＇, Day 1, every times 1000 mLo Treatment gr6up received fresh frozen plasma 200 ml, once a day,Control group albu- min 10 g, once daily. The end of rehydration, Intravenous furosemide 40 mg,Treatment for 10 days. Results Two groups of patients before and after the serum biochemical indicators of liver and kidney function has declined, And the treatment group Compared with the control group, Between the two groups before and after treatment, Were statistically significant. Liver and kidney dysfunction in patients with treatment group was significantly less than the conventional group（P〈0.05）. The method has good application value.