胃癌的病理与预后:200例中晚期胃癌病理分析

对200例胃癌切除标本病理分析并对其中的147例随访,其五年生存率是23.5%。胃癌的预后因素与肿瘤的浸润深度、淋巴结转移和肿瘤细胞的分化成熟程度有明显关系。11例肿瘤已浸润达浆膜层者生存了五年以上,1例生存十余年,这表明手术切除肿瘤、药物治疗及改善机体免疫状态可以提高五年生存率。

A PATHOLOGICAL ANALYSIS OF 200 CASES OF PROGRESSING GASTRIC CARCINOMA

Two hundred specimens of progressing gastric carcinoma collectedfrom 1967-1977 were studied morphologically. There were 1/17 patients withfollow up and the survival rate of 5 years was 23.5% The pathological findingswere evaluated in relation to prognosis. It was found that the survival rate of5 years is related to the depth of infiltration, lymph nodes metastasis anddegree of differentiation of the tumor cells. In 11 cases, the cancer hasinfiltrated the serosa the patients survived up to 5 years and more. Amongthose there were 7 cases with metastasis to the regional lymph nodes. One ofthese patients is living and well over 10 years after the operation. The reasonthat patients with advanced carcinoma could survive for more than 5 years ispossibly due to increased immunity against tumor growth.