Alveolar bone and the bisphosphonates |
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Authors: | A Cheng,CG Daly&dagger ,RM Logan&Dagger ,B Stein§ ,AN Goss |
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Affiliation: | Oral and Maxillofacial Surgery Unit, The University of Adelaide, South Australia.; Periodontology, The University of Sydney, New South Wales.; Oral Pathology, The University of Adelaide, South Austalia.; Ashford Cancer Centre and The University of Adelaide, South Australia. |
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Abstract: | Bisphosphonate associated osteonecrosis of the jaws (ONJ) usually commences at the alveolus. Comparison is made between the structure and function of long bones and alveolar bone and the differing susceptibilities of the bisphosphonates at these different sites are explored. Current concepts of the causation of ONJ are discussed. The clinical implications of these findings to dentists managing periodontal conditions are presented. |
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Keywords: | Alveolar bone bone diseases bisphosphonates osteonecrosis of the jaws |
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