双介入治疗肝肿瘤的临床应用

目的探讨采用穿刺引流抽吸肝肿瘤中心坏死物(DTND)和经动脉化疗栓塞(TACE)治疗肝肿瘤的疗效。方法明显液化坏死的原发性巨块型肝癌4例,消化道间叶细胞来源肝转移瘤1例。患者先行肝TACE术,随后行DTND。4例行坏死物持续负压引流,1例反复多次抽吸。在引流或抽吸同时向瘤腔内注入无水乙醇。结果4例持续引流者肿瘤缩小明显,抽吸者肿瘤略缩小。5例均未出现并发症。结论PTND结合肝TACE术是治疗液化坏死肝肿瘤安全、可行的方法。

Double interventional treatment for hepatic tumor through percutaneous tumor necrosis drainage and transcatheter arterial chemoembolization

Objective To discuss the therapeutic effectiveness of combined percutaneous tumor necrosis drainage(PTND) and TACE for the treatment of hepatic tumor with obvious liquefaction necrosis.Methods Four primary massive types of liver cancer with obvious liquefaction necrosis and the other one of hepatic metastases from mesenchymal tumor of digestive tract received TACE first,and PTND was performed afterwards.Continuous drainge was performed in 4 patients,while repeated aspiration in one.Absolute ethanol was injected into the tumor necrotic cavitives during the procedure of drainge or aspiration.Results Obvious reduction in tumor size occurred in 4 patients receiving continuous drainage,while slight reduction was obtained in the patient treated by repeated aspiration.No complication occurred in all 5 patients.Conclusion PTND combined with TACE is safe and effective for treating hepatic tumor with obvious liquefaction necrosis.