| 创伤性颅脑损伤标志物的研究进展 |
| |
| 引用本文： | 叶继业,刘绍明.创伤性颅脑损伤标志物的研究进展[J].医学综述,2012(20):3350-3352. |
| |
| 作者姓名： | 叶继业 刘绍明 |
| |
| 作者单位： | 石河子大学医学院;兰州军区乌鲁木齐总医院神经外科 |
| |
| 摘 要： | 创伤性颅脑损伤(TBI)严重危害人类的生活和健康,在众多创伤性疾病中最易引起患者残疾和死亡。如何客观、快速、准确、早期对TBI做出诊断和严重程度分级,对TBI的临床治疗和预后起着重要作用。颅脑损伤标志物在损伤早期就可出现在血清和脑脊液中,其敏感性和特异性往往比影像学检查更具优势。现就常见的TBI标志物研究现状和实际应用情况予以综述。
|
| 关 键 词： | 创伤性颅脑损伤 S100β蛋白 神经元特异性烯醇化酶 神经胶质纤维酸性蛋白 髓磷脂碱性蛋白 Tau蛋白 |
Research Progress of Markers of Traumatic Brain Injury |
| |
| YE Ji-ye,LIU Shao-ming.Research Progress of Markers of Traumatic Brain Injury[J].Medical Recapitulate,2012(20):3350-3352. |
| |
| Authors: | YE Ji-ye LIU Shao-ming |
| |
| Institution: | 1.Medical College of Shihezi University,Shihezi 832002,China;2.Department of Neurosurgery,Urumqi Military General Hospital of Lanzhou Region,Urumqi 830000,China) |
| |
| Abstract: | Traumatic brain injury(TBI)causes great damage to people′s life and health,and it could most likely lead to disability and death in many traumatic diseases.How to make a quick,accurate and objective diagnosis in the early stage is quite important for the clinical treatment and prognosis.Biomedical markers of TBI appear early in the serum and cerebro-spinal fluid with a higher sensitivity and specificity than image examination.Here is to make a brief review on the commonly seen TBI markers based on the current studies and applications. |
| |
| Keywords: | Traumatic brain injury S100β protein Neuron-specific enolase Glial fibrillary acidic potein Myelin basic protein Tau protein |
| 本文献已被 CNKI 等数据库收录！ |
