输入性恶性疟疾2例流行病学及临床分析

目的探讨输入性恶性疟疾的流行病学和临床特征。方法对2010年10月至2012年7月收治住院的2例输入性恶性疟疾患者的流行病学资料、临床表现、实验室检查、诊治情况进行回顾性分析。结果 1例患者为非洲劳务回国的中年男性,另1例患者是曾去上海世博会旅游的青年男性,均有贫血、脾大、肝功能异常,1例白细胞减少,1例血小板减少。经抗疟治疗后,2例均在短期(1～2周)内治愈出院。结论输入性恶性疟疾患者临床表现复杂,对输入性恶性疟疾患者应及时进行外周血涂片,认真查找疟原虫,明确诊断,抗疟治疗,避免凶险型疟疾的发生。

Epidemiological and clinical analysis of two cases of imported pernicious malaria

Objective To study epidemiological and clinical features of imported pernicious malaria. Methods Epidemiological data. clinical manifestations, laboratory examinations, diagnosis and treatments of 2 cases of patient with pernicious malaria hospitalized in this hospital in October, 2010 to July, 2012 in this hospital were retrospective analysis. Results One patient was a middle-aged labor man returning from Africa, and the other young man had been to the Shanghai Expo. All of them were with anemia, splenomegaly and liver dysfunction. One patient developed leucopenia, and the other one developed thrombocytopenia. After antimalarial treatment, both of them were cured in the short term（1-2 weeks）. Conclusion Patients with imported pernicious malaria might be with complex clinical manifestations. According to individuals return from Africa or from affected areas, clinical staff should combine the epidemiological and clinical characteristics, take high degree of vigilance of imported pernicious malaria, perform pe- ripheral blood smear timely, find plasmodium seriously, confirm the diagnosis, take antimalarial treatment and avoid dangerous malaria occurrence.