Clinical and magnetic resonance imaging findings in chronic sensory ganglionopathies |
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Authors: | Lauria G Pareyson D Grisoli M Sghirlanzoni A |
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Institution: | Department of Neurology, National Neurological Institute C Besta, Milan, Italy. |
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Abstract: | Twenty-two of 29 patients with chronic sensory ataxic neuropathy showed T2-weighted magnetic resonance imaging high signal intensity in the posterior columns of the cervical spine. T2 changes reflected the degeneration of central sensory projections and localized the disease process to T-shaped dorsal root ganglion neurons. No similar abnormalities were found in sensory and sensorimotor length-dependent axonal neuropathy patients. Spinal cord magnetic resonance imaging is a useful tool to support the clinical diagnosis of primary ganglionopathy. |
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