| 经门静脉注入碘油化疗药治疗肝癌的实验研究 |
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| 引用本文： | 刘鹏程,郭俊渊,王承缘,胡国栋,黄志程,刘绍春.经门静脉注入碘油化疗药治疗肝癌的实验研究[J].华中科技大学学报(医学版),1994(4). |
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| 作者姓名： | 刘鹏程 郭俊渊 王承缘 胡国栋 黄志程 刘绍春 |
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| 作者单位： | 同济医科大学附属同济医院放射科!武汉430030(刘鹏程，郭俊渊，王承缘，胡国栋，黄志程)，同济医科大学基础医学院病理解剖教研室!武汉4300(刘绍春) |
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| 摘 要： | 20只实验性肝癌大白鼠和20只正常大白鼠经门静脉注入碘油混悬液，在光学显微镜下观察碘油混悬液在肝脏的分布。结果在癌巢内、癌巢内小血管、肝窦及及中央静脉均见有碘油滴。表明门静脉参与肝癌的血供，经门静脉注入碘油化疗药混悬液可致肝癌细胞坏死，提示对肝癌除了经肝动脉化疗和栓塞外，还可辅以经门静脉的化疗和碘油栓塞。
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| 关 键 词： | 肝肿瘤 实验性 门静脉 灌注法 局部药物疗法 碘油 |
Effect of Iodized Oil and Chemotherapeutic Agents Given via Portal Vein on Hepatic Carcinoma:Study with Animal Model |
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| Liu Pengcheng,GuoJunyuan,Wang Cheng yuan,et al.Effect of Iodized Oil and Chemotherapeutic Agents Given via Portal Vein on Hepatic Carcinoma:Study with Animal Model[J].Journal of Huazhong University of Science and Technology(Health Sciences),1994(4). |
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| Authors: | Liu Pengcheng GuoJunyuan Wang Cheng yuan |
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| Institution: | Liu Pengcheng,GuoJunyuan,Wang Cheng yuan,et alDepartment of Radiology,Tongji Hospital,Tongjl Medical University,Wuhan 430030 |
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| Abstract: | Microscopic examination was carried out after injection of iodized oil into pro-tal veins of 20 rats with hepatic carcinoma and 20 normal rats to observe its distribution in the liver.Oil drops were seen in tumor cell lines,small blood vessels inside the cancer nest,the sinusoids,and the central veins.The results showed that protal vein involved in the blood supply of liver cancer and tumor cell necrosis can be achieved after administration of iodized oil and anticancer agent mixture through the protal vein.Transcatheter treatment through the portal vein may be helpful as a supplement to intraarterial treatment of primary liver cancer. |
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| Keywords: | liver neoplasms experimental portal vein perfusion regional iodized olis |
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