男性系统性红斑狼疮76例临床分析

目的提高对男性系统性红斑狼疮（SLE）特点的认识。方法回顾性分析76例男性SLE及同期住院，年龄、病程相配的76例女性SLE的临床特征。结果与女性SLE相比，男性SLE患者的发病年龄、初发症状、主要临床表现基本相似。但其面部蝶形红斑发生率较低（P＜0．05），中枢神经损害、肾脏损害、血小板减少发生率较高，发病后5年内的病死率较高（P＜0．05）。结论男性和女性SLE的临床表现和预后是有差别的。

Clinical study of 76 male patients with systematic lupus erythematosus

Objective: To study the characteristics of systematic lupus erythematosus in male. Methods CIinical features in 76 male patients with systematic lupus erythematosus (MSLE) and 76 female patients with systematic lupus erythematosus(FSLE) were analysed for reviewing. Results FSLE and MSLE patients were at almost the same age at the time of disease onset,and had the similar symptoms and major clinical features. However,MSLE patients and lower chance of developing malar resh (P<0. 05),but higher incidence of neurological and renal damages and thrombocytopenia than FSLE patients. The analysis also showed that the male patients had higher case mortality in the five years after the disease onset (P<0.05 ). Conclusiou There is difference in the clinical features and the prognosis be tween MSLE and FSLE.