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元胡提取液3种纯化方法的对比研究
引用本文:魏舒畅,冯晓莉,张英明,金辉.元胡提取液3种纯化方法的对比研究[J].中国药房,2010(39):3691-3692.
作者姓名:魏舒畅  冯晓莉  张英明  金辉
作者单位:[1]甘肃中医学院,兰州市730000 [2]兰州佛慈制药有限公司,兰州市730000
摘    要:目的:对比研究找到纯化元胡提取液的最佳方法。方法:以除杂率、延胡索乙素保留率为评价指标,并比较纯化后样品的物理性质,用于评价超滤法、天然澄清剂法与乙醇沉淀法在元胡提取液纯化工艺中的可行性。结果:超滤法除杂率高,所得样品品质最好。结论:采用超滤法纯化元胡提取液最具可行性。

关 键 词:元胡  乙醇沉淀法  天然澄清剂  超滤

Comparative Study on the 3 Kinds of Purification Processes for the Extract of Corydalis yanhusuo
WEI Shu-chang,FENG Xiao-li,JIN Hui.Comparative Study on the 3 Kinds of Purification Processes for the Extract of Corydalis yanhusuo[J].China Pharmacy,2010(39):3691-3692.
Authors:WEI Shu-chang  FENG Xiao-li  JIN Hui
Institution:(Gansu College of Traditional Chinese Medicine,Lanzhou 730000,China) ZHANG Ying-ming(Lanzhou Foci Pharmaceutical Co.,Ltd.,Lanzhou 730000,China)
Abstract:OBJECTIVE:To optimize the purification process for the extract of Corydalis yanhusuo by comparative study.METHODS:The feasibility of 3 kinds of purification processes(ultrafiltration,ethanol precipitation and natural clarifier) was evaluated by comparing the physical character of purified samples with using the retention rate of corydalis B and the rate of removed impurity as index.RESULTS:The rate of removed impurity was the highest and the quality of samples was the best by ultrafiltration method among 3 kinds of methods.CONCLUSION:Ultrafiltration is the best purification process for the extract of C.yanhusuo.
Keywords:Corydalis yanhusuo  Ethanol precipitation  Natural clarifier  Ultrafiltration
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