经典恒温加速法预测0.5%戊二醛溶液的稳定性

目的:考察0.5%戊二醛溶液的稳定性。方法:采用经典恒温加速法和留样观察法,以戊二醛的含量为考察指标,采用滴定法测定其含量。结果:0.5%戊二醛溶液的含量变化符合一级动力学过程,2种考察方法的结果基本一致。在室温(25℃)条件下,其有效期为85.7d。结论:0.5%戊二醛溶液应尽快使用,2周内是其最佳使用时间。

Stability Predictions of 5% Glutaraldehyde Solution Using Classic Constant Temperature Accelerated Test Method

OBJECTIVE： To investigate the stability of 0.5% glutaraldehyde solution. METHODS： Classic constant temperature accelerated test method and sample observation method were applied with the content of glutaraldehyde as index. The content of glutaraldehyde was determined by titration which was determined by titration. RESULTS： The content change of 0.5% glutaraldehyde solution was in line with the first order kinetics, and the results of both methods were similar. The validity duration of 0.5% glutaraldehyde solution was 85.7 days at room temperature （25 ℃）. CONCLUSION： 0.5% glutaraldehyde solution should be used up as soon as possible and the perfect time is less than 2 week.