依达拉奉联合银杏达莫治疗急性脑梗死的临床疗效及对神经功能的影响

目的:观察依达拉奉联合银杏达莫治疗急性脑梗死的临床疗效及对神经功能的影响。方法:74例急性脑梗死患者随机分为2组:对照组37例,给予银杏达莫注射液20mL加入5%葡萄糖注射液250mL静脉滴注,qd;观察组37例,在对照组治疗基础上给予依达拉奉注射液30mg加入0.9%氯化钠100mL静脉滴注,bid。观察比较2组治疗前后的临床疗效、神经功能缺损程度及血脂水平的变化。结果:观察组的有效率明显高于对照组,差异有统计学意义(P<0.05)。2组治疗后14、21d神经功能缺损程度评分均较治疗前明显下降,差异有统计学意义(P<0.05),且观察组评分均低于同期对照组,差异有统计学意义(P<0.05)。结论:依达拉奉联合银杏达莫治疗急性脑梗死能够明显提高临床疗效,改善患者神经功能状态。

Clinical Efficacy of Edaravone Combined with Yinxing Damo in Treatment of Acute Cerebral Infarction and Effect on Neurologic Function

OBJECTIVE：To observe clinical efficacy of edaravone combined with Yinxing damo in treatment of acute cerebral infarction and effect on neurologic function.METHODS：74 cases of acute cerebral infarction were randomly divided into 2 groups （n=37）.Observation group were treated with edaravone combined Yinxing damo and control group were treated with Yinxing damo only.Clinical efficacy,neurologic function defection and the level of blood lipid of 2 groups were compared.RESULTS：Effective rate in observation group was significantly higher than in control group,there were statistical significance in difference between 2 groups （P0.05）.Neurologic function defection scores of 2 groups were significantly decreased at 14th day,21th day after treatment,there were statistical significance （P0.05）.Neurologic function defection scores of observation group were significantly lower than that of control group at 14th day,21th day after treatment,there were statistical significance （P0.05）.CONCLUSION：Edaravone combined with Yinxing damo have good effect on acute cerebral infarction to improve clinical efficacy neurologic function.