| 不同厂家药品微生物限度检查用计数培养基的质量比较 |
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| 引用本文： | 朱斌,刘涛,蒋受军,章艳. 不同厂家药品微生物限度检查用计数培养基的质量比较[J]. 中国药房, 2010, 0(25): 2365-2368 |
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| 作者姓名： | 朱斌 刘涛 蒋受军 章艳 |
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| 作者单位： | [1]广西壮族自治区食品药品检验所,南宁市530021 [2]桂林医学院,桂林市541004 |
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| 摘 要： | 目的:对不同厂家药品微生物限度检查用细菌、真菌计数培养基的部分质量指标进行比较。方法:以市售的常见品牌及实验室自制的共7种营养琼脂和5种玫瑰红钠琼脂培养基为对象,测定其水分、含氮量、pH值等理化指标,并用5株代表菌株进行加菌回收计数,比较生长菌落数量及菌落大小。结果:不同厂家的培养基理化指标、加菌回收的菌落数量和菌落大小均有差异。结论:不同厂家培养基质量存在一定差异,培养基的理化指标与培养基质量有一定相关性。
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| 关 键 词： | 厂家 微生物限度检查 培养基 质量比较 |
Quality Comparison of Counting Culture Medium of Drugs Microbial Limit Test from Different Manufacturers |
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| ZHU Bin,LIU Tao,JIANG Shou-jun,ZHANG Yan. Quality Comparison of Counting Culture Medium of Drugs Microbial Limit Test from Different Manufacturers[J]. China Pharmacy, 2010, 0(25): 2365-2368 |
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| Authors: | ZHU Bin LIU Tao JIANG Shou-jun ZHANG Yan |
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| Affiliation: | (Guangxi Institute for Food and Drug Control,Nanning 530021,China;Guilin Medical University,Guilin 541004,China) |
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| Abstract: | OBJECTIVE：To compare the quality of fungus and bacteria counting culture medium of drug microbial limit test among different manufacturers.METHODS：Culture medium for 7 kinds of nutrient agars and 5 kinds of sodium rose red bengal agars for sale or self-made were enrolled in study.The content of water and nitrogen,pH value were determined.The number of microcolonies which were recovered from 5 kinds of representative bacterial strains was calculated,and the size and number of microcolonies were compared.RESULTS：Physicochemical index of culture medium,the size and number of microcolonies were different among different manufacturers.CONCLUSION：The quality of culture medium is different among different manufacturers,which is associated with physicochemical index. |
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| Keywords: | Manufacturers Microbial limit test Culture medium Quality comparison |
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