| 复方苦芩软膏质量标准研究 |
| |
| 引用本文： | 张沂,王强,蔡清宇,任婷麟,于春令,郝特,吴迪.复方苦芩软膏质量标准研究[J].中国药房,2010(19):1781-1783. |
| |
| 作者姓名： | 张沂 王强 蔡清宇 任婷麟 于春令 郝特 吴迪 |
| |
| 作者单位： | 海军总医院药剂科,北京市100048 |
| |
| 摘 要： | 目的:对复方苦芩软膏的质量标准进行研究。方法:采用薄层色谱法对方中芦荟苷、黄芩苷、薄荷脑进行定性鉴别;采用高效液相色谱法测定制剂中黄芩苷及延胡索乙素的含量。结果:定性鉴别方法专属性强。延胡索乙素的线性范围为0.131～3.275μg(r=0.9999),平均回收率为102.40%,RSD=0.77%(n=6);黄芩苷的线性范围为0.05035～2.014μg(r=0.9999),平均回收率为100.97%,RSD=1.42%(n=6)。结论:本方法简便、准确,重复性好,可用于复方苦芩软膏的质量控制。
|
| 关 键 词： | 复方苦芩软膏 延胡索乙素 黄芩苷 质量标准 薄层色谱法 高效液相色谱法 |
Study on Quality Standards of Compound Kuqin Ointment |
| |
| ZHANG Yi,WANG Qiang,CAI Qing-yu,REN Ting-lin,YU Chun-ling,HAO Te,WU Di.Study on Quality Standards of Compound Kuqin Ointment[J].China Pharmacy,2010(19):1781-1783. |
| |
| Authors: | ZHANG Yi WANG Qiang CAI Qing-yu REN Ting-lin YU Chun-ling HAO Te WU Di |
| |
| Institution: | (Dept.of Pharmacy,Navy General Hospital of PLA,Beijing 100048,China) |
| |
| Abstract: | OBJECTIVE：To study the quality standards of Compound kuqin ointment.METHODS：TLC method was used for the identification of alion,baicalin,menthol.The content of tetrahydropalmatine and baicalin were determined by HPLC.RESULTS：The identification method was specific.The linear range of tetrahydropalmatine was 0.131～3.275 μg（r=0.999 9） with an average recovery of 102.40%（RSD=0.77%,n=6）.The linear range of baicalin was 0.050 35～2.014 μg （r=0.999 9）with an average recovery of 100.97%（RSD=1.42%,n=6）.CONCLUSION：The method is simple,accurate and reproducible for the quality control of Compound kuqin ointment. |
| |
| Keywords: | Compound kuqin ointment Tetrahydropalmatine Baicalin Quality standards TLC HPLC |
| 本文献已被 维普 等数据库收录！ |
|
