| 双黄解毒乳膏质量标准研究 |
| |
| 引用本文： | 聂继红,王萍,夏昌隆,马建红.双黄解毒乳膏质量标准研究[J].中国药房,2010(31):2918-2920. |
| |
| 作者姓名： | 聂继红 王萍 夏昌隆 马建红 |
| |
| 作者单位： | [1]新疆医科大学附属中医医院,乌鲁木齐市830000 [2]新疆药物研究所,乌鲁木齐市830004 |
| |
| 基金项目： | 新疆维吾尔自治区科技攻关和重点科技项目资助课题（200333112B1） |
| |
| 摘 要： | 目的:建立双黄解毒乳膏的质量标准。方法:采用薄层色谱法对制剂中的黄芩和关黄柏进行定性鉴别;采用高效液相色谱法对制剂中的黄芩苷含量进行定量分析。结果:定性鉴别方法能同时鉴别黄芩、关黄柏,专属性强,分离度好。黄芩苷进样浓度在80.0～400.0μg·mL-1范围内与峰面积积分值呈良好线性关系(r=0.9998);平均回收率为97.3%,RSD=1.3%(n=9)。结论:所建标准可用于双黄解毒乳膏的质量控制。
|
| 关 键 词： | 双黄解毒乳膏 质量标准 薄层色谱法 高效液相色谱法 |
Quality Standard of Shuanghuang Jiedu Cream |
| |
| NIE Ji-hong,WANG Ping,XIA Chang-longThe Affiliated Hospital of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi,China MA Jian-hong.Quality Standard of Shuanghuang Jiedu Cream[J].China Pharmacy,2010(31):2918-2920. |
| |
| Authors: | NIE Ji-hong WANG Ping XIA Chang-longThe Affiliated Hospital of Traditional Chinese Medicine Xinjiang Medical University Urumqi China MA Jian-hong |
| |
| Institution: | NIE Ji-hong,WANG Ping,XIA Chang-long(The Affiliated Hospital of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi 830000, China) MA Jian-hong(Xinjiang Institute of Materia Medica, Urumqi 830004, China) |
| |
| Abstract: | OBJECTIVE： To establish the quality standard of Shuanghuang jiedu cream. METHODS： Scutellaria baicalensis and Phellodendron chinensis were identified qualitatively by TLC and the content of baicalin was determined by HPLC. RESULTS： The qualitative identification can be used to identify S. baicalensis and P. chinensis simultaneously. It is specific and well separated. The linear range of baicalin were 80.0 μg·mL-1 and 400.0 μg·mL-1（r=0.999 8）with an average recovery of 97.3% （RSD=1.3%,n=9）. CONCLUSION： Established method be used for the quality control of Shuanghuang jiedu cream. |
| |
| Keywords: | Shuanghuang jiedu cream Quality standard TLC HPLC |
| 本文献已被 维普 等数据库收录！ |
