| 灵芝颗粒质量标准研究 |
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| 引用本文： | 薛强,李卿,秦剑,肖铭玉.灵芝颗粒质量标准研究[J].中国药房,2010(39):3722-3724. |
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| 作者姓名： | 薛强 李卿 秦剑 肖铭玉 |
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| 作者单位： | [1]重庆医科大学附属第二医院,重庆市400010 [2]重庆市中药研究院,重庆市400065 |
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| 摘 要： | 目的:建立灵芝颗粒的质量标准。方法:采用薄层色谱(TLC)法对方中灵芝、柴胡进行定性鉴别;采用高效液相色谱法测定五味子中五味子甲素、五味子乙素含量。结果:TLC斑点清晰,分离度好,阴性对照无干扰;五味子甲素进样量、五味子乙素进样量分别在0.060～0.60、0.082～0.82μg范围内与各自峰面积积分值呈良好线性关系(r分别为0.9996、0.9995);平均回收率分别为99.02%、99.06%,RSD分别为0.45%(n=6)、0.48%(n=6)。结论:定性定量方法快速、准确、专属性强,所建标准可用于灵芝颗粒的质量控制。
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| 关 键 词： | 灵芝颗粒 薄层色谱法 高效液相色谱法 灵芝 柴胡 |
Study on Quality Standard of Lingzhi Granules |
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| XUE QiangThe Second Affiliated Hospital of Chongqing Medical University,Chongqing,China LI Qing,QIN Jian,XIAO Ming-yu.Study on Quality Standard of Lingzhi Granules[J].China Pharmacy,2010(39):3722-3724. |
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| Authors: | XUE QiangThe Second Affiliated Hospital of Chongqing Medical University Chongqing China LI Qing QIN Jian XIAO Ming-yu |
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| Institution: | (Chongqing Academy of Chinese Materia Medica,Chongqing 400065,China) |
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| Abstract: | OBJECTIVE：To establish the quality standard of Lingzhi granules.METHODS：The qualitative identification of Ganoderma and Bupleuri Radix was carried out by TLC.The content of deoxyschizandrin and γ-Schisandrin in Schisandra chinensis was determined by HPLC.RESULTS：The TLC sports were fairy clear and separated well without interference of negative sample.The linear ranges were 0.060～0.60 μg for deoxyschizandrin（r=0.999 6）,0.082～0.82 μg for γ-Schisandrin（r=0.999 5）,respectively.The average recoveries were 99.02%（RSD=0.45%,n=6） and 99.06%（RSD=0.48%,n=6）.CONCLUSION：The method is rapid,accurate and specific.It can be used for the quality control of Lingzhi granules. |
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| Keywords: | Lingzhi granules TLC HPLC Ganoderma Bupleuri Radix |
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