| 厚术胶囊质量标准研究 |
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| 引用本文： | 林秋晓,刘秋琼,刘晓琦,李英,陈妙芬. 厚术胶囊质量标准研究[J]. 中国药房, 2010, 0(23): 2184-2186 |
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| 作者姓名： | 林秋晓 刘秋琼 刘晓琦 李英 陈妙芬 |
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| 作者单位： | 广东省人民医院药学部／广东省医学科学院,广州市510080 |
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| 摘 要： | 目的:建立厚术胶囊的质量标准。方法:采用薄层色谱(TLC)法对方中苍术、三七、白芍和山楂药材进行定性鉴别;采用高效液相色谱法测定厚朴中厚朴酚、和厚朴酚的含量。结果:TLC斑点清晰,阴性对照无干扰。厚朴酚与和厚朴酚的进样量分别在0.080～0.400μg(r=0.9999)、0.048～0.240μg(r=0.9999)范围内与各自峰面积积分值呈良好的线性关系;平均回收率分别为98.42%、98.34%,RSD分别为0.63%、0.90%(n=6)。结论:所建标准可有效控制厚术胶囊的质量。
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| 关 键 词： | 厚术胶囊 质量标准 厚朴酚 和厚朴酚 薄层色谱法 高效液相色谱法 |
Study on Quality Standard of Houshu Capsules |
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| LIN Qiu-xiao,LIU Qiu-qiong,LIU Xiao-qi,LI Ying,CHEN Miao-fen. Study on Quality Standard of Houshu Capsules[J]. China Pharmacy, 2010, 0(23): 2184-2186 |
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| Authors: | LIN Qiu-xiao LIU Qiu-qiong LIU Xiao-qi LI Ying CHEN Miao-fen |
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| Affiliation: | (Pharmaceutical Department of Guangdong Municipal People’s Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China) |
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| Abstract: | OBJECTIVE： To establish the quality standard of Houshu capsules.METHODS： TLC was used to identify Atractylodes lancea,Panax notoginseng,Paeonia lactiflora and Crataegus pinnatifida.The content of magnolol and honokiol in Magnolia officinalis was determined by HPLC.RESULTS： TLC spots were clear without interference of negative substance.The linear range were 0.080～0.400 μg for magnolol and 0.048～0.240 μg for honokiol （r=0.999 9）.The average recovery were 98.42% for magnolol （RSD=0.63%,n=6） and 98.34% for magnolol （RSD=0.90%,n=6）.CONCLUSION： Established quality standard can be applied for the quality control of Houshu capsules. |
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| Keywords: | Houshu capsules Quality standard Magnolol Honokiol TLC HPLC |
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