| 应用2008年WHO新分类分析骨髓增生异常综合征患者186例 |
| |
| 引用本文： | 王玉春,杜欣.应用2008年WHO新分类分析骨髓增生异常综合征患者186例[J].临床血液学杂志,2010(3). |
| |
| 作者姓名： | 王玉春 杜欣 |
| |
| 作者单位： | 广东省人民医院（广东省医学科学院）肿瘤中心血液科;南方医科大学; |
| |
| 摘 要： | 目的:应用2008年WHO髓系肿瘤新分类法,对既往诊断的骨髓增生异常综合征(MDS)患者重新分类,了解各亚型的临床和实验室检查特点。方法:回顾性分析186例MDS患者初发病时的临床表现、血常规、骨髓象、骨髓病理学和细胞遗传学等方面的临床特点。RCUD34例,RARS19例,RCMD22例,RAEB-162例,RAEB-237例,MDS-U9例,5q-3例。并进行电话随访,追踪其临床病情进展情况。对随访结果结合临床资料应用SPSS13.0软件包进行数据处理。结果:按照新分型标准,34例RCUD中,RA12例,RN19例,RT13例,186例MDS患者中位发病年龄为62岁,资料齐全的随访病例123例,中位生存期30.2个月,各亚型中位生存期分别为RCUD84个月,RARS50个月,RCMD40个月,RAEB-117个月,RAEB-211个月,MDS-U69个月,RCUD、RARS、RCMD及MDS-U的中位生存期与RAEB-1、RAEB-2差异有统计学意义(P<0.05)。已确诊转化为急性髓系白血病共14例,其中12例死亡,转白后中位生存期仅4个月。结论:新分型标准中RCUD包含原有的RA亚型,新增加RN、RT亚...
|
| 关 键 词： | 骨髓增生异常综合征 WHO分型 国际预后积分系统 |
Clinical analysis of 186 cases of myelodysplastic syndrome according to the new WHO classification |
| |
| WANG Yuchun DU Xin.Clinical analysis of 186 cases of myelodysplastic syndrome according to the new WHO classification[J].Journal of Clinical Hematology,2010(3). |
| |
| Authors: | WANG Yuchun DU Xin |
| |
| Institution: | Department of Hematology/a>;Cancer Center/a>;Guangdong General Hospital/a>;Guangdong Academy of Medical Sciences/a>;Guangzhou/a>;510080/a>;China |
| |
| Abstract: | Objective:To investigate the clinical and laboratorial characters of myelodysplastic syndrome (MDS) according to the new 2008 WHO classification.Method:186 patients diagnosed with MDS was observed retrospectively over past 8 years. The features of morphologic,clinical,cytogenetic and overall survival data was analyzed. SPSS 13.0 software was used to analyze the data.Result:According to the new 2008 WHO classification,there were 34 cases of RCUD inchuding 12 RA,19 RN and 13 RT. The median age of patients was... |
| |
| Keywords: | myelodysplastic syndromes WHO classification international prostate symptom score |
| 本文献已被 CNKI 等数据库收录！ |
|
