| 微循环, 纳米医学的研究平台 |
| |
| 引用本文： | 李爱玲,修瑞娟. 微循环, 纳米医学的研究平台[J]. 国际病理科学与临床杂志, 2008, 28(3): 19-276 |
| |
| 作者姓名： | 李爱玲 修瑞娟 |
| |
| 作者单位： | 中国医学科学院,北京协和医学院,微循环研究所,北京100005 |
| |
| 基金项目： | 国家重点基础研究发展计划(973计划) |
| |
| 摘 要： | 微循环作为机体最小的循环单位，极大地影响纳米药物的运输、代谢,成为纳米医学研究的重要平台；特别是微血管内皮细胞在纳米医学的靶向性研究、安全性检测和疾病诊断中发挥了重要作用，推动了肿瘤及其他微血管相关疾病的诊断、治疗。建立纳米医学的微循环检测平台，对纳米药物的临床可应用性进行评估亟待进行。
|
| 关 键 词： | 纳米医学 微循环 内皮细胞 |
| 收稿时间： | 2007-11-19 |
| 修稿时间： | 2008-02-19 |
Microcirculation, the study plateform for nanomedicine |
| |
| LI Ai-ling,XIU Rui-juan. Microcirculation, the study plateform for nanomedicine[J]. Journal of International Pathology and Clinical Medicine, 2008, 28(3): 19-276 |
| |
| Authors: | LI Ai-ling XIU Rui-juan |
| |
| Affiliation: | Institute of Microcirculation,Chinese Academy Medical Sciences &Peking Union Medical College, Beijing 100005,China |
| |
| Abstract: | As the least circulatory unit, microcirculation affects the delivery and metabolism of drugs greatly, and has become the important responsive stage of nanomedicine research. Especially the discovery of protein markers expressed by micro-vascular endothelium and its targeting role in nanomedicine research improved the possibility in diagnosis and therapy of diseases including tumor, vascular-related diseases and so on.It is necessary to establish the detective platform of microcirculation about nanomedicine for evaluation of the clinical availability of nano-drug. |
| |
| Keywords: | nanomedicine microcirculation endothelium |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《国际病理科学与临床杂志》浏览原始摘要信息 |
|
点击此处可从《国际病理科学与临床杂志》下载全文 |
|
