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聚乙二醇滴眼液治疗干眼症的疗效观察
引用本文:李杰,庞彦英,李坤.聚乙二醇滴眼液治疗干眼症的疗效观察[J].中国药房,2012(2):138-140.
作者姓名:李杰  庞彦英  李坤
作者单位:河北沧州市中心医院药剂科;沧州眼科医院;河北沧州市中心医院眼科
摘    要:目的:探讨聚乙二醇滴眼液治疗干眼症的疗效。方法:60例干眼症患者分为A组与B组,各30例。A组给予聚乙二醇滴眼液滴眼,B组给予0.05%羧甲基纤维素滴眼液滴眼。连续用药1周后评价疗效,并记录患者干眼症状的变化及记录泪液分泌试验(SIT)、泪膜破裂时间(BUT)结果。结果:2组眼部各症状较治疗前均有改善;2组治疗前、后SIT值差异无统计学意义;A组BUT明显较B组延长,并且在120min时差异具有显著性。结论:聚乙二醇滴眼液是一种长效缓解干眼的有效药物。

关 键 词:干眼症  泪膜破裂时间  聚乙二醇滴眼液

Efficacy Observation of Polyethylene Glycol Eye Drops in the Treatment of Xerophthalmia
LI JieDept.of Pharmacy,Cangzhou Municipal Central Hospital of Hebei Province,Hebei Cangzhou,China PANG Yan-yingCangzhou Eye Hospital,Hebei Cangzhou,China LI Kun.Efficacy Observation of Polyethylene Glycol Eye Drops in the Treatment of Xerophthalmia[J].China Pharmacy,2012(2):138-140.
Authors:LI JieDeptof Pharmacy  Cangzhou Municipal Central Hospital of Hebei Province  Hebei Cangzhou  China PANG Yan-yingCangzhou Eye Hospital  Hebei Cangzhou  China LI Kun
Institution:LI Jie(Dept.of Pharmacy,Cangzhou Municipal Central Hospital of Hebei Province,Hebei Cangzhou 061001,China) PANG Yan-ying(Cangzhou Eye Hospital,Hebei Cangzhou 061001,China) LI Kun(Dept.of Ophthalmology,Cangzhou Municipal Central Hospital of Hebei Province,Hebei Cangzhou 061001,China)
Abstract:OBJECTIVE:To probe into the therapeutic efficacy of Polyethylene glycol(PEG) eye drops in the treatment of xerophthalmia.METHODS:60 patients with xerophthalmia were divided into group A and group B with 30 patients for each group.Group A and B were treated with PEG eye drops and 0.05% Carboxymethyl cellulose eye drops,respectively.Therapeutic efficacy was evaluated after continuous treatment of 1 weak.The symptom changes of patients and the results of SIT test and BUT test were recorded.RESULTS:The eye’s symptoms of 2 groups were improved after treatment.There was no significant difference in the results of SIT test between 2 groups before and after treatment.However,PEG eye drops was better than 0.05% Carboxymethyl cellulose eye drops in improving the breakup time of tear film,and there was significant difference at 120 min.CONCLUSION:PEG eye drops is a long-acting effective eye drops for xerophthalmia.
Keywords:Xerophthalmia  Breakup time of tear film  Polyethylene glycol eye drops
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