镇痛膏的药效学实验研究

目的：观察镇痛膏镇痛抗炎及改善微循环作用。方法：实验动物外用镇痛膏（巴布贴），观察本品对炎症反应、局部疼痛及微循环的影响。结果：镇痛膏对小鼠热板性疼痛能提高基痛阈值，有明显的镇痛作用；对小鼠二甲苯致耳廓肿，大鼠蛋清性中趾肿有明显抗炎作用；对小鼠肠系膜微循环有明显改善作用。结论：镇痛膏具有明显镇痛，抗炎、改善微循环作用。

PHARMACODYNAMIC RESEARCH OF ANALGESIC-PASTE

Objective: To observe the analgesic, anti inflammatory and microcirculation improving actions of analgesic paste. Method: The analgesic paste(babutie) is applied to observe its effect on inflammation, local pain and microcirculation. Results: The analgesic paste can raise the threshold of hot plate pain in mice, showing obvious analgesic action. There are marked anti inflammation effects in mice against pavilion swelling caused by xylene and in rats against toes swelling caused by albumen. The Analgesic paste can improve the mesentery microcirculation in mice. Conclusions: There are analgesic, anti inflammatory, and microcirculation improving actions in the analgesicpaste.