Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma |
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| Authors: | Xiao-Dong Bu Nan Li Xiao-Qiang Tian Li Li Jin-Song Wang Xiao-Jin Yu Pei-Lin Huang |
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| Affiliation: | Xiao-Dong Bu, Nan Li, Xiao-Qiang Tian, Pei-Lin Huang, Department of Pathology, School of Medicine, Southeast University, Nanjing 210009, Jiangsu Province, China;Li Li, Jin-Song Wang, Department of Pathology, Nanjing First Hospital of Nanjing Medical University, Nanjing 210006, Jiangsu Province, China;Xiao-Jin Yu, Department of Epidemiology and Statistics, School of Public Health, Southeast University, Nanjing 210009, Jiangsu Province, China |
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| Abstract: | AIM:To study the expression profiles of MUC2 and MUC5AC in tumorigenesis of colorectal carcinoma and in its different pathologic types.METHODS:Formalin-fixed,paraffin-embedded human colorectal tissue specimens were immunostained with antibodies against MUC2 and MUC5AC.Six samples of normal mucosa(NM),12 samples of hyperplastic polyp(HP),15 samples of tubular adenoma with low-grade dysplasia(LGD),14 samples of tubular adenoma with high-grade dysplasia(HGD),26 samples of conventional colorectal adenocarcinoma... |
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| Keywords: | Colorectum Tumorigenesis MUC2 MUC5AC Immunohistochemistry |
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