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Hepatocellular carcinoma in patients with chronic hepatitis C virus infection without cirrhosis
Authors:Kathryn L Nash   Tracy Woodall   Ashley SM Brown   Susan E Davies     Graeme JM Alexander
Affiliation:Department of Hepatology University of Cambridge Addenbrooke s Hospital Hills Road Cambridge CB2 2QQ United Kingdom Mailpoint 255 Southampton General Hospital Tremona Road Southampton Hampshire SO16 6YD Liver Unit Department of Medicine St Mary s Hospital Praed Street London W2 1NY Department of Histopathology
Abstract:AIM:To investigate and characterise patients with chronic hepatitis C virus(HCV) infection presenting with hepatocellular carcinoma(HCC) in the absence of cirrhosis.METHODS:Patients with chronic hepatitis C infection without cirrhosis presenting with HCC over a 2-year period were identified.The clinical case notes,blood test results and histological specimens were reviewed to identify whether additional risk factors for the development of HCC were present.RESULTS:Six patients(five male,one female) with chro...
Keywords:Hepatitis C virus   Hepatocellular carcinoma   Non-cirrhotic   Screening
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