Expression of protein S100A4 is a predictor of recurrence in colorectal cancer |
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Authors: | Jung Myun Kwak Hyun Joo Lee Seon Hahn Kim Han Kyeom Kim Young Jae Mok Young Tae Park Jong Sang Choi Hong Young Moon |
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Affiliation: | Department of Surgery Korea University Anam Hospital Department of Pathology Korea University Guro Hospital Department of Gastroenterology Korea Uni-versity Guro Hospital |
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Abstract: | AIM: To investigate the prognostic significance of S100A4 expression in colorectal cancer and its correlation with expression of E-cadherin and p53. METHODS: A cohort of archival formalin-fixed paraff inembedded specimens was selected from 127 patients with colorectal cancer who underwent surgical resection between April 2000 and March 2004 at the Department of Surgery, Korea University Guro Hospital. The expression of protein S100A4 was evaluated according to the proportion of positively stained cancer cel... |
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Keywords: | S100A4 E-cadherin p53 Prognostic factor Colorectal cancer |
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