南京市城区居民体力活动与2型糖尿病罹患风险关系的随访研究

目的 探讨南京市城区居民体力活动与2型糖尿病罹患风险之间的关系.方法 于2004年和2007年分别在南京市抽取5个居委会,以所抽取的居委会中35岁以上常住居民为研究对象.研究内容主要包括慢性疾病罹患情况及相关生活行为因素,使用国际体力活动量表测量体力活动情况.对完成有效基线调查效对象5 659人进行为期3年的随访研究,采用多因素Logistic回归模型分析体力活动与2型糖尿病罹患风险之间的关系.结果 有效随访4 550人,随访率为80.4％.充足体力活动的比例为16.5％ (753/4 550),2型糖尿病的3年累计发病率为5.1％ (95％CI=4.48,5.80).充足体力活动者其罹患2TD的风险显著低于体力活动不足者的罹患风险,只约为后者的一半(RR =0.45,95％CI=0.31,0.77),这种关联在男女性人群中也分别存在.结论 充足体力活动都可以显著降低人们罹患2型糖尿病的风险,倡导充足体力活动是2型糖尿病社区防制的可性和有效策略之一.

Relationship between physical activity and risk of type 2 diabetes in urban adults of Nanjing:a pooled study from two 3-year community-based prospective cohorts

OBJECTIVE To investigate the relationship between physical activity and the risk of type 2 diabetes(T2D)in urban adults of Nanjing,China.METHODS Two community-based adult prospective cohort studies were respectively conducted during 2004-2007 and 2007-2010 in urban areas of Nanjing.T2D was defined by World Health Organization criteria based on physicians’ diagnosis and fasting blood glucose concentration.Physical activity,parental diabetes history,and covariates were assessed at baseline and in the third-year follow-up survey.The data analyzed in 2011 were pooled from above mentioned two studies.RESULTS In the 4 550 urban adults,the three-year cumulative incidence of T2D was 5.1%.The proportion of sufficient physical activity was 16.5%(753/4 550).Compared to their counterparts with insufficient physical activity,participants with sufficient physical activity were at a significant lower risk of developing T2D(RR = 0.45,95%CI = 0.31,0.77).Such relationship was observed in both men and women.CONCLUSION Sufficient physical activity can reduce the risk of developing T2D.It is of great significance to initiate community-based physical activity promotion in the campaign against T2D in urban adults.