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Clinical and Serological Analysis of a Q Fever Outbreak in Western Slovakia with Four-Year Follow-Up
Authors:E Kováčová  J Kazár  A Šimková
Institution:(1) Institute of Virology, Slovak Academy of Sciences, Dúbravská cesta 9, 842 46 Bratislava, Slovak Republic e-mail: virukova@savba.sk,;(2) Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic,;(3) Regional Hospital, Zlaté Moravce, Slovak Republic,
Abstract: In the spring of 1993, an outbreak of respiratory infection affected 113 persons (103 males) in Jedl'ové Kostol'any, a village located in a hilly area of western Slovakia. Q fever, manifested as a flu-like illness with atypical pneumonia and hepatic involvement, was diagnosed using four serological tests (microimmunofluorescence, microagglutination, complement fixation, and enzyme immunoassay). Aborting goats were proven as a source of infection. During a 4-year follow-up study, no chronic form of Q fever could be demonstrated, either clinically or by tests to detect phase I Coxiella burnetii antibodies.
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