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Automated model-based vertebra detection,identification, and segmentation in CT images
Authors:Tobias Klinder  Jörn Ostermann  Matthias Ehm  Astrid Franz  Reinhard Kneser  Cristian Lorenz
Institution:1. Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland;2. Institute of Physical Activity and Nutrition Research, Deakin University, Burwood, Victoria, Australia;3. Charité University Medical School Berlin, Germany;4. University of Ljubljana, Slovenia;5. Stanford University, USA;6. University of Exeter, The United Kingdom;7. Imperial College London, The United Kingdom;8. The Chinese University of HongKong, China;9. Sectra, Linköping, Sweden;10. Case Western Reserve University and University Hospitals Case Medical Center, USA;11. University of Queensland, Australia;12. The Australian e-Health Research Centre, CSIRO Health and Biosecurity, Australia;13. Graz University of Technology, Austria;14. Ludwig Boltzmann Institute for Clinical Forensic Imaging, Austria;15. VRVis Center for Virtual Reality and Visualization, Austria;p. University of Western Ontario, Canada
Abstract:For many orthopaedic, neurological, and oncological applications, an exact segmentation of the vertebral column including an identification of each vertebra is essential. However, although bony structures show high contrast in CT images, the segmentation and labelling of individual vertebrae is challenging.In this paper, we present a comprehensive solution for automatically detecting, identifying, and segmenting vertebrae in CT images. A framework has been designed that takes an arbitrary CT image, e.g., head-neck, thorax, lumbar, or whole spine, as input and provides a segmentation in form of labelled triangulated vertebra surface models. In order to obtain a robust processing chain, profound prior knowledge is applied through the use of various kinds of models covering shape, gradient, and appearance information. The framework has been tested on 64 CT images even including pathologies. In 56 cases, it was successfully applied resulting in a final mean point-to-surface segmentation error of 1.12 ± 1.04 mm.One key issue is a reliable identification of vertebrae. For a single vertebra, we achieve an identification success of more than 70%. Increasing the number of available vertebrae leads to an increase in the identification rate reaching 100% if 16 or more vertebrae are shown in the image.
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