超声引导下胸膜腔注入尿激酶治疗结核性胸腔积液

目的探讨超声引导下胸膜腔注入尿激酶治疗结核性多房性胸腔积液的临床价值。方法对42例结核性胸腔积液患者超声引导下注入生理盐水50ml稀释的尿激酶10万IU,24小时后抽尽液体,如仍有积液与分隔,重复上述治疗。结果第1次注入尿激酶后抽液量较用药前明显增多,第2~4次用药后抽液量增多不明显。总有效率为95.2%。结论超声引导下胸膜腔注入尿激酶是治疗结核性胸腔积液一种安全有效的方法。

Treatment with ultrasound-guided drainage and urokinase injection for tuberculous pleural effusion

Objective To study the value of treating tuberculous pleural effusion with ultrasound-guided drainage intracavitary urokinase.Methods Forty-two tuberculous pleural effusion patients were treated with ultrasound-guided drainage and with intrapleural injection of 100,000IU urokinase (diluted by 50ml normal saline). Twenty-four hours later, the drainage was repeated. The procedure was repeated until there were no septal and pleural fluid collection. Results The aspiration volume before urokinase injection was significiantly defferent from that after the first time injection. No significiant difference was found from the second to the fourth time. The overall efficiency rate was 95.2%. Conclusion Ultrasound-guided drainage with adjunctive pleural urokinase therapy is a safe and effective method in treating tuberculous pleural effusion.