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| 多囊卵巢综合征性激素变化与认知功能的临床观察 | |
| 引用本文： | 刘锦霞,段立晖,吴静静,于淼,吴元赭,吴效科.多囊卵巢综合征性激素变化与认知功能的临床观察[J].医学研究生学报,2008,21(11). |
| 作者姓名： | 刘锦霞 段立晖 吴静静 于淼 吴元赭 吴效科 |
| 作者单位： | 1. 南京军区南京总医院,妇产科,江苏南京,210002 2. 南京军区南京总医院,干部神经科,江苏南京,210002 3. 黑龙江中医药大学附属第一医院妇产科,黑龙江哈尔滨,150040 |
| 基金项目： | 国家"十一五"科技支撑计划基金资助项目 |
| 摘 要： | 目的:研究多囊卵巢综合征(PCOS)患者认知功能的变化,并探讨其与雄激素的关系. 方法:选择PCOS患者(PCOS组)及健康自愿者(对照组)各25例,放射免疫测定其血浆睾酮(T)、硫酸脱氢表雄酮(DHEAS)、性激素结合蛋白(SHBG)、雌二醇(E2)、卵泡刺激素(FSH)和黄体生成素(LH). 认知功能测定包括词语学习及延迟回忆、言语流畅性、符号数字替代模式、连线测验A、数字广度和积木测验. 结果:PCOS组患者血中T、 LH、 SHBG 与对照组比较差异有显著性统计学意义(P＜0.01);其动物言语流畅性测验和连线测验A较对照组显著性下降(P＜0.05). 结论:PCOS患者存在认知功能损害,这可能与其血中雄激素增高有关. |
| 关 键 词： | 多囊卵巢综合征 认知功能 |
A clinical study of the cognitive function of patients with polycystic ovary syndrome |
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| LIU Jin-xia,DUAN Li-Hui,WU Jing-jing,YU Miao,WU Yuan-zhe,WU Xiao-ke.A clinical study of the cognitive function of patients with polycystic ovary syndrome[J].Bulletin of Medical Postgraduate,2008,21(11). | |
| Authors: | LIU Jin-xia DUAN Li-Hui WU Jing-jing YU Miao WU Yuan-zhe WU Xiao-ke |
| Institution: | LIU Jin-xia1,DUAN Li-Hui2,WU Jing-jing1,YU Miao1,WU Yuan-zhe1,WU Xiao-ke3(1.Department of Obstetrics , Gynecology,2.Department of Geriatric Neurology,Nanjing General Hospital of Nanjing Military Comm,,PLA,Nanjing 210002,Jiangsu,China,3.Department of Obstetrics , Gynecology,The Affiliated Hospital of Heilongjiang University of Chinese Traditional Medicine,Harbin 150040,Heilongjiang,China) |
| Abstract: | Objective: To observe the changes of the cognitive function of patients with polycystic ovary syndrome(PCOS) and explore their relationship with serum testosterone.Methods: The levels of serum testosterone(T),dehydroepiandrosterone sulfate(DHEAS),sex hormone binding globulin(SHBG),Estradiol(E2),follicle-stimulating hormone(FSH) and luteotrophic hormone(LH) were measured by radioimmunity assay in 25 patients with PCOS and 25 normal women.Their cognitive functions were assessed by delayed word recall test,wor... |
| Keywords: | Polycystic ovary syndrome Cognitive function |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |