四川地区成人血清缺血修饰清蛋白参考区间的建立

目的建立四川地区成人血清缺血修饰清蛋白(IMA)的参考区间。方法选择四川地区800名健康体检者,采用游离钴比色法测定IMA的含量,利用百分位数法(非参数法)评估参考区间,以97.5%百分位数作为单侧参考区间上限。结果 (1)男、女两组IMA水平分别为小于78.1U/mL和小于77.5U/mL,两组差异无统计学意义(P>0.05);(2)Ⅰ组血清IMA水平为小于77.3U/mL,Ⅱ组血清IMA水平为小于77.6U/mL,Ⅲ组血清IMA水平为小于78.4U/mL。3组之间两两比较,差异均无统计学意义(P>0.05)。结论四川地区成人血清IMA的参考区间是小于77.8U/mL,与性别、年龄无关。

The establishment of the reference interval of ischemia modified albumin of adult in Sichuan area

Objective To establish the adult reference interval of ischemia modified albumin in Sichuan area.Methods 800 healthy physical examination samples were selected,their serum IMA concentration was determined by Free Cobalt Method.And we used percentile method（nonparametric） to evaluate reference interval,within 97.5% percentile as unilateral reference interval high limit.Results（1）IMA level of men was 〈78.1 U/mL and women was 〈77.5 U/mL,there was no statistically significant difference between the two groups（P〉0.05）.（2）IMA level of group Ⅰ was 〈77.3 U/mL,IMA level of group Ⅱ was 〈77.6 U/mL,IMA level of group Ⅲ was 〈78.4 U/mL.The difference was not statistically significant by pairwise comparison method.Conclusion In Sichuan area,the adult reference interval of IMA is 〈77.8 U/mL,it is irrelevant with age and sex.