常见临床病原微生物分布及其耐药性分析

目的探讨该院2010年10月至2011年9月临床感染的菌群分布情况及其耐药性。方法细菌鉴定采用手工法，药敏试验采用纸片扩散法。结果共分离细菌491株，以革兰阴性茵为主（65．2％），分离率以大肠埃希菌最高，革兰阴性杆菌对抗菌药物敏感率最高的是亚胺培南，革兰阳性球菌中未分离出耐万古霉素的菌株。结论临床科室应根据微生物实验室所提供的细菌耐药情况，合理使用抗茵药物。

Distribution and drug resistance analysis of common pathogenic microorganism

Objective To explore the distribution and drug resistance of common pathogenic microorganism in this hospital from Oct 2010 to Nov 2009.Methods Manual method was used for bacteria appraisal and diffusion method was used for the pieces of drug sensitive test.Results 491 strains of pathogens were isolated,most of those were Gram-negative bacterium,the highest Separation rate was Escherichia coli,the highest of antibacterial agent sensitive rate for Gram-negative bacterium was not imipenem,vancomycin-resistant strain was isolated in Gram-positive cocci.Conclusion Clinical laboratory should rationally use antibiotics according to resistance situation for the bacteria.