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冠心病患者超敏C反应蛋白及总胆红素检测的临床意义
引用本文:钟志娟,许坚锋,陈红涛,李冬梅,郭国威.冠心病患者超敏C反应蛋白及总胆红素检测的临床意义[J].检验医学与临床,2012(20):2544-2545.
作者姓名:钟志娟  许坚锋  陈红涛  李冬梅  郭国威
作者单位:中山大学附属第五医院检验科 ,广东珠海 519000
摘    要:目的探讨冠心病(CHD)患者血清总胆红素及超敏C反应蛋白(hs-CRP)测定的临床意义。方法 60例冠心病患者及健康对照60例,用钒酸盐氧化法测定总胆红素,用透射比浊法测定hs-CRP浓度并做结果分析。结果冠心病患者血清总胆红素水平与健康对照组相比降低(P〈0.05),hs-CRP水平与健康对照组相比增高(P〈0.01)。结论血清总胆红素与冠心病的发生率呈负相关;血清C-反应蛋白与冠心病的发生率呈正相关。

关 键 词:冠心病  血清总胆红素  超敏C反应蛋白

Clinical significance of serum total bilirubin and Hs-CRP in patients with coronary heart disease
ZHONG Zhi-juan,XU Jian-feng,CHEN Hong-tao△,LI Dong-mei,GUO Guo-wei.Clinical significance of serum total bilirubin and Hs-CRP in patients with coronary heart disease[J].Laboratory Medicine and Clinic,2012(20):2544-2545.
Authors:ZHONG Zhi-juan  XU Jian-feng  CHEN Hong-tao△  LI Dong-mei  GUO Guo-wei
Institution:(Department of Clinical Laboratory,Fifth Affiliated Hospital,Sun Yat-sen University,Zhuhai,Guangdong 519000,China)
Abstract:Objective To investigate the clinical significance of serum total bilirubin and high sensitivity C-reactive protein(hs-CRP) in the patients with coronary heart disease(CHD).Methods The serum levels of total bilirubin and hs-CRP were respectively determined by the vanadium-acid oxidation method and the transmission turbidimetry in 60 cases of CHD(CHD group) and 60 healthy individuals(control group).Results The serum level of total bilirubin in the CHD group was decreased as compared with the healthy group(P<0.05),while the serum level of Hs-CRP was increased as compared with the healthy group(P<0.001).Conclusion There is negative correlation between serum total bilirubin level and the occurrence of CHD.There is positive correlation between hs-CRP and the occurrence of CHD.
Keywords:coronary heart disease  total bilirubin  high sensitivity C-reactive protein
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