| 肾移植术后发生高尿酸血症的机制 |
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| 引用本文： | 刘锋,张艮甫,姬西宁,黄赤兵,王平贤,范明齐. 肾移植术后发生高尿酸血症的机制[J]. 临床泌尿外科杂志, 2004, 19(8): 465-466 |
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| 作者姓名： | 刘锋 张艮甫 姬西宁 黄赤兵 王平贤 范明齐 |
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| 作者单位： | 解放军第161中心医院泌尿外科,武汉,430010;第三军医大学附属新桥医院肾移植中心 |
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| 摘 要： | 目的：探讨肾移植术后发生高尿酸血症的机制及防治策略。方法：分析480例肾移植术后患者的临床资料。结果：肾移植术后移植肾功能正常而血尿酸增高者43例(9％)，其中痛风7例，移植肾肾盂或输尿管结石3例。随访1～5年，1例痛风患者血尿酸及症状控制不理想，余血尿酸均控制在正常水平，未见并发症的发生。结论：高尿酸血症是肾移植术后较常见的问题，发生原因较多，但主要与环孢素A的作用有关；长期降尿酸及碱化尿液治疗安全、有效。
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| 关 键 词： | 肾移植 高尿酸血症 痛风 |
| 文章编号： | 1001-1420(2004)08-0465-02 |
| 修稿时间： | 2003-12-30 |
Hyperuricemia after renal transplantation |
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| LIU Feng ZHANG Genfu JI Xilin HUANG Chibing WANG Pingxian FAN Mingqi. Hyperuricemia after renal transplantation[J]. Journal of Clinical Urology, 2004, 19(8): 465-466 |
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| Authors: | LIU Feng ZHANG Genfu JI Xilin HUANG Chibing WANG Pingxian FAN Mingqi |
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| Affiliation: | LIU Feng1 ZHANG Genfu1 JI Xilin2 HUANG Chibing1 WANG Pingxian1 FAN Mingqi1 |
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| Abstract: | Objective:To evaluate the mechanism and therapeutic strategy of hyperuricemia after renal transplantation.Methods:The clinical data of 43 patients of hyperuricemia after renal transplantation from October 1998 to October 2002 were analyzed.Results:There were 43(9%) in the 480 patients were diagnosed hyperuricemia but the function of allograft were normal, 7 patients(1.5%)suffered from gout, 3 patients with urinary tract calculi. 43 patients were followed up from 1 to 5 years , blood uric acid and symptom were controlled effectively except 1 case.Conclusions:Hyperuricemia is a common problem of renal transplant recipients, its prevalence is mainly attributable to CsA use. The urate lowering and urine basifying therapy are safe and effective. |
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| Keywords: | Kidney transplantation Hyperuricemia Gout |
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