暴发性肝功能衰竭预后高危因素的分析

目的:探讨暴发性肝功能衰竭(fulminanthepaticfailure,FHF)预后不良的高危因素。方法:回顾了53例不同预后的FHF患者的年龄、病原学、并发症和实验室检查指标与预后的关系。结果:年龄小则预后较好。并发症与病情危险相关因素由高到低依次为:肝肾综合征>出血>感染>腹水,血清AST/ALT、TBil/DBil、TBA、Tch水平比较可见:前三项死亡组高于存活组,Tch则为存活组高于死亡组;PTA<40%、APTT>45s的患者存活率相对较低。结论:年龄、并发症情况、肝功能和凝血象指标是反映FHF患者预后的重要因素。

Analyzing the risk factors of the prognosis of fulminant hepatic failure

Objective: To explore the risk factors of the bad prognosis of fulminant hepatic failure.Methods: We analyzed the relation between prognosis and age,etiologic feature,complication,index of laboratory examination.Results: The survival rate were more higher in the younger patients.The serum levels of AST/ALT,TBil/Dbil,TBA were significantly higher in the death group than in the survival group.The level of Tch was contrary.The survival rate was significantly higher in patients whose PTA>40%,and similar result was obtained in patients whose APTT<45 seconds.Conclusion: The age,the complication and the index of the laboratory examination are the important factors in judging the prognosis of fulminant hepatic failure.