脑白质疏松症的CT诊断与临床关系探讨(附145例分析)

目的探讨脑白质疏松症的发病机理及CT表现与临床症状的关系,为临床诊断和治疗提供可靠依据。方法回顾性分析145例脑白质疏松症的CT及临床表现。结果脑白质疏松症的CT表现为双侧侧脑室额角和/或枕角周围对称性低密度区、双侧侧脑室周围斑片状对称性低密度区或脑白质弥漫性低密度区。此病尚可合并有基底节、丘脑腔隙性梗塞及出血。结论脑白质疏松症常发生于双侧侧脑室额角和枕角周围,严重病例可累及双侧侧脑室周围全部脑白质区。本病病理基础为双侧侧脑室周围白质脱髓鞘,其决定因素可能为脑白质的血供特点及高血压。

CT diagnosis and clinical of leukoaraosis(with 145 cases report)

Objective To investigate pathogenesis of leukoaraosis, the correlation between CT presentation and clinical symptom and to provide useful evidance for clinical diagnosis and treatment. Methods CT presentation and clinical symptoms in the Leukoaraosis of 145 cases were retrospectively analyzed. Results Leukoaraosis manifested symmetrical hypo- dense lesion adjacent to frontal horn and/or occipital horn of bilateral ventricles; symmetrical hypo- dense peri- ventricle patches; or diffuse hypo- dense white matter.Lacunar infarction or hemorrhage of basal ganglion and/or thalamies may alse be revealed. Conclusion Leukoaraosis often involves the white matter adjacent to the frontal horn and occipital horn of bilateral ventrieles.And entire peri- ventricle white matter may be affectel in severe cases.The pathology of the disease is related to demyelination of brain white matter, resulting in the characteristic vascularity in white matter,which may alter under hypertension.