青春期糖尿病雄鼠血清生化组分分析

目的：以雄性大鼠为观察对象，探讨糖尿病对青春期血清生化成分变化的影响。方法：采用日本日立牌７１５０型生化自动分析仪（Ｈｉｔａｃｈｉ７１５０Ａｕｔｏｍａｔｉｃａｎａｌｙｚｅｒ）测试。结果：血清ＡＬＢ、ＴＰ、ＰＡ、ＣＲＥ、Ｐ、Ｃａ、ＩＣＤＨ在各组间比较没有显著差异；ＵＡ、ＢＵＮ、ＴＢＡ、ＧＰＴ、ＬＡＰ、ＣＫ、ＡＫＰ、ＴＡＣＰ在Ｃ（对照组），ＤＣＩＲ（胰岛素及时治疗糖尿病），ＤＤＩＲ（胰岛素延迟治疗糖尿病）和Ｄ（糖尿病）组中依次升高，而ＴＧ、ＣＨＯ和ＧＯＴ只在Ｄ组显著升高。结论：胰岛素及时治疗效果明显优于延迟治疗

Analysis of serum biochemistry compositionsin puberty rats with diabetes

Objective:To study the effect of diabetes on the changes of serum biochemistry compositions using male Wistar rats as abservation target.Methods:All of results were determined by the use of Hitachi 7150 automatic biochemistry analyzer.Results:There were no significant differences in the concentrations of serum ALB,TP,PA,CRE,P,CA and activity of ICDH among 4 groups;the level of serum UA,BUN,TBA and the activities of CPT,LAP,CK,AKP,TACP progressively inceased in order of C (control), DCIR (diabetes with continuons insulin replacement),DDIR (Diabetes with delayed insulin replacement),and D (diabetes) groups;the levels of serum TG,CHO and GOT were significantly higher than that of C.Conclusion:Effect of DCIR was significantly better than that of DDIR.