Immediate breast reconstruction with expander in pregnant breast cancer patients |
| |
| Authors: | Visnu Lohsiriwat Fedro Alessandro Peccatori Stefano Martella Hatem A Azim Maria Anna Sarno Viviana Galimberti Francesca De Lorenzi Mattia Intra Claudia Sangalli Nicole Rotmensz Giancarlo Pruneri Giuseppe Renne Mario Casales Schorr Luiz Felipe Nevola Teixeira Mario Rietjens Massimo Giroda Oreste Gentilini |
| |
| Institution: | 1. Division of Plastic Surgery, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;2. Faculty of Medicine, Mahidol University, Siriraj Hospital, Bangkok, Thailand;3. Fertility and Procreation in Oncology Unit, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;4. Breast Surgery Department, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;5. Epidemiology Department, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;6. Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;7. Pathology Department, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;8. University of Milan School of Medicine, Italy;9. Physiotherapy Unit, European Institute of Oncology, Via Ripamonti, 435 – 20141 Milano, Italy;10. Division of Surgery, Fondazione IRCCS Ca'' Granda, Via F Sforza, 28-20122 Milano, Italy;1. Department of Naval, Electrical, and ICT Engineering, University of Genoa, Via Opera Pia 11a, I-16145 Genova, Italy;2. ABB—Power System Division, Via Albareto 35, I-16153 Genova, Italy;1. Clinique de Genolier, Switzerland;2. Leiden University Medical Center, The Netherlands;3. Medical School, University of Athens, Athens, Greece;4. Ontario Institute for Cancer Research, Toronto, Canada;5. Weston Park Hospital NHS Trust, Sheffield, United Kingdom;1. Nuclear Medicine Department, Germans Trias i Pujol University Hospital, Carretera del Canyet, Badalona, Spain;2. Oncology Department, Catalan Institute of Oncology, Germans Trias i Pujol University Hospital, Carretera del Canyet, Badalona, Spain;3. Pathology Department, Germans Trias i Pujol University Hospital, Carretera del Canyet, Badalona, Spain;4. Radiology Department, Germans Trias i Pujol University Hospital, Carretera del Canyet, Badalona, Spain;5. Surgery Department, Germans Trias i Pujol University Hospital, Carretera del Canyet, Badalona, Spain;6. Gynecology Department, Germans Trias i Pujol University Hospital, Carretera del Canyet, Badalona, Spain;1. Department of Surgery, Jeroen Bosch Ziekenhuis, P.O. Box 90153, 5200 ME ''s-Hertogenbosch, The Netherlands;2. Department of Radiology, Jeroen Bosch Ziekenhuis, ''s-Hertogenbosch, The Netherlands;3. Department of Pathology, Jeroen Bosch Ziekenhuis, ''s-Hertogenbosch, The Netherlands;4. Department of Oncology, Jeroen Bosch Ziekenhuis, ''s-Hertogenbosch, The Netherlands |
| |
| Abstract: | BackgroundBreast reconstruction after mastectomy is currently considered an essential component in managing breast cancer patients, particularly those diagnosed at a young age. However, no studies have been published on the feasibility of immediate breast reconstruction in patients diagnosed and operated during the course of gestation.MethodWe retrospectively identified all breast cancer patients who were subjected to mastectomy and immediate breast reconstruction during pregnancy at the European Institute of Oncology between 2002 and 2012. Patient demographics, gestational age at surgery, tumor stage, adjuvant treatment, details of the surgical procedures, surgical outcomes and fetal outcomes were analyzed.ResultsA total of 78 patients with breast cancer diagnosed during pregnancy were subjected to a surgical procedure during the course of gestation. Twenty-two patients had mastectomy; of whom 13 were subjected to immediate breast reconstruction. Twelve out of 13 patients had a two-stage procedure with tissue expander insertion. Median gestational age at surgery was 16 weeks. No major surgical complications were encountered. Only one patient elected to have an abortion, otherwise, no spontaneous abortions or pregnancy complications were reported. Median gestational age at delivery was 35 weeks (range: 32–40 weeks). No major congenital malformations were reported. At a median follow-up of 32 months, all patients are alive with no long-term surgical complications.ConclusionsThis is the first study of immediate breast reconstruction in pregnant breast cancer patients. Tissue expander insertion appears to ensure a short operative time, and does not seem to be associated with considerable morbidity to the patient or the fetus. Hence, it could be considered in the multidisciplinary management of women diagnosed with breast cancer during pregnancy. |
| |
| Keywords: | Breast cancer Pregnancy Immediate reconstruction Mastectomy |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
