室内燃料燃烧的废气致突变性研究

经研究,长期从事家庭炊事劳动而接触烧煤、液化石油气、木柴废气的调查居民,其浓缩尿样的致突变率分别为90.9％、82.6％、30.8％,且主要是对TA98起致突变作用。从三种燃料燃烧的废气所诱导居民外周血红细胞的微核率差异,经统计分析无显著性,在用燃烧的液化石油气废气给小白鼠经呼吸道动式染毒的亚慢性试验中,用肺组织匀浆作Ames和骨髓嗜多染红细胞微核试验,其所得的结果表明该废气具有明显的致突变作用。

STUDY ON THE MUTAGENIC EFFECT OF INDOORAIR POLLUTION FROM COMBUSTION EMISSION IN COOKING

The mutagenic rates of urine concentrates of the survey subjects engaged in cooking and exposed to three kinds of lurning wastes (coal, liguified petroleum gas and firewood) were 90.9%, 82.6% and 30.8% respectfively.And the mutations were mainly restricted to lacterial strain TA98 in Ames test. But the study of induced micronucleus in periphery red tlood cells showed no statistic difference among the three types. The mutagenic effects of the turning waste of liguified petroleum gas was also investigated throngh murine test of breathe tract contamination.The results of Ames test (done with lung homogenate) and micro-nucleus test (done with bone marrow polychomatoerythorocyte) both indicated that the waste was highly mutagenetic.