| 单克隆抗体对唾液凝集素介导的茸毛链球菌(S.sobrinus)聚集的影响 |
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| 引用本文： | 张平,樊明文,边专,杜民权,李成章. 单克隆抗体对唾液凝集素介导的茸毛链球菌(S.sobrinus)聚集的影响[J]. 华西口腔医学杂志, 1999, 17(3): 0-223 |
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| 作者姓名： | 张平 樊明文 边专 杜民权 李成章 |
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| 作者单位： | 湖北医科大学口腔医学院,湖北医科大学口腔医学院,湖北医科大学口腔医学院,湖北医科大学口腔医学院,湖北医科大学口腔医学院 |
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| 摘 要： | 目的；用制备的抗茸毛链球菌主要表面蛋白的单克隆抗体作用于茸毛链球菌，体外观察单克隆抗体对唾液凝集素介导的细菌聚集的影响。方法；于紫外分光光度计上通过光密度值检测１ｈ内的细胞凝集情况。结果：单克隆抗体对唾液凝集素介导的茸毛链球菌之间的聚集有一定程度的影响，但作用不明显。
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| 关 键 词： | 单克隆抗体 茸毛链球菌 |
| 收稿时间： | 1999-06-25 |
| 修稿时间： | 1999-06-25 |
Effects of Monoclonal Antibody Against the Major Cell Surface Protein on Salivary Agglutinin Mediated Aggregation of Streptococcus sobrinus |
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| Zhang Ping,Fan Mingwen,Bian Zhuan,et al College of Stomatology,Hubei Medical University. Effects of Monoclonal Antibody Against the Major Cell Surface Protein on Salivary Agglutinin Mediated Aggregation of Streptococcus sobrinus[J]. West China journal of stomatology, 1999, 17(3): 0-223 |
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| Authors: | Zhang Ping Fan Mingwen Bian Zhuan et al College of Stomatology Hubei Medical University |
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| Affiliation: | College of Stomatology, Hubei Medical University. |
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| Abstract: | Objective: To investigate the effects of monoclonal antibody on salivary agglutinin mediated aggregation of Streptococcus sobrinus in vitro. Methods: Bacterial aggregation inhibition was measured under OD-{650 at 10 minutes intervals for 1 hour. Results: It showed that the McAb ZS2/286 raised against the PAg of S.sobrinus 6715 could inhibit the aggregation by some degree, but the effect was not significant. Conclusion: The McAb ZS2/286 might not bind directly to the functionally important region of PAg related to aggregation. |
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| Keywords: | monoclonal antibody aggregation Streptococcus sobrinus |
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