Abstract: | Adipose tissue is not only an organ for storing fat,but also an important endocrine tissue in the body.Many active substances secreted by it,such as adiponectin,leptin,tumor necrosis factor and resistin,are involved in many physiological and pathological processes in the human body,which play an important role in maintaining the body''s metabolic balance,including glucose,lipid metabolism and energy balance,especially in the process of insulin resistance(IR) formation.Studies have shown that the most important intervention in early diabetes is to improve insulin resistance,and low levels of adipocytokines are one of the causes of the development of diabetes.The relationship between several important adipocytokines and pre-diabetes and diabetes and diabetic complications and its research progress are described below. |