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Regression of superficial gastric MALT lymphoma with unsuccessful eradication therapy forHelicobacter pylori infection
Authors:Hiroaki Yoshikane  Takio Yokoi  Hitoshi Hidano  Akira Sakakibara  Yasumasa Niwa  Hidemi Goto
Affiliation:1. Department of Internal Medicine, Handa City Hospital, 2-29 Toyo, Handa, 475, Aichi, Japan
2. Division of Pathology, Aichi Medical University, Aichi, Japan
3. Second Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Japan
Abstract:A 51-year-old man had a reddish flat granular lesion in the stomach on endoscopic examination. Histology of biopsied specimen confirmed the diagnosis of low-grade B-cell gastric lymphoma of mucosaassociated lymphoid tissue (gastric MALT lymphoma) and simultaneous infection withHelicobacter pylori. He was given antibiotic treatment. Five weeks later, endoscopy and histology of biopsied specimen showed eradication ofH. pylori, and the tumor had regressed. Six months later,H. pylori reemerged, but the tumor had not recurred. After the second antibiotic therapy,H. pylori has been eradicated. The lymphoma has been in remission for 14 months.
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