| 结肠慢传输型便秘与突触素和 P物质及血管活性肠肽的临床研究 |
| |
| 引用本文： | 丁义江,哈楠林,丁曙晴,徐文华,耿建祥. 结肠慢传输型便秘与突触素和 P物质及血管活性肠肽的临床研究[J]. 中华胃肠外科杂志, 2004, 7(6): 485-487 |
| |
| 作者姓名： | 丁义江 哈楠林 丁曙晴 徐文华 耿建祥 |
| |
| 作者单位： | 210001,南京中医药大学附属南京市中医院,全国中医肛肠专科医疗中心 |
| |
| 摘 要： | 目的探讨突触素(synapses,SY)、P物质(substanceP,SP)和血管活性肠肽(vasoactiveintestinepolypeptide,VIP)在结肠慢传输型便秘(slowtransitconstipation,STC)中的变化及病理学意义。方法应用免疫组织化学技术和病理显微镜分析图像系统,在中倍光镜下计算22例STC患者(STC组)和12例非梗阻性结直肠癌患者(对照组)的阳性染色区域的面积并进行对比。结果STC组患者结肠内SY、VIP和SP镜下阳性面积均较对照组明显减少。STC组和对照组SY分别为[(1.53±0.92)×105]μm2和[(3.33±1.09)×105]μm2;两组比较,P<0.001。SP分别为[(1.41±0.85)×105]μm2和[(2.22±1.31)×105]μm2,两组比较,P<0.05。VIP分别为[(1.22±0.72)×105]μm2和[(2.14±1.35)×105]μm2,两组比较P<0.05。结论STC患者存在肠神经系统突触功能障碍,从而导致肠神经递质下降。
|
| 关 键 词： | 结肠慢传输型便秘 突触素 P物质 血管活性肠肽 |
| 修稿时间： | 2004-02-20 |
Synapses,substance P and vasoactive intestine polypeptide in slow transit constipation |
| |
| DING Yi jiang,HA Nan lin,DING Shu qing,XU Wen hua,GENG Jian xiang. Affiliated Nanjing Traditional Chinese Medicine Hospital,Nanjing Traditional Chinese Medicine University,Nanjing ,China. Synapses,substance P and vasoactive intestine polypeptide in slow transit constipation[J]. Chinese journal of gastrointestinal surgery, 2004, 7(6): 485-487 |
| |
| Authors: | DING Yi jiang HA Nan lin DING Shu qing XU Wen hua GENG Jian xiang. Affiliated Nanjing Traditional Chinese Medicine Hospital Nanjing Traditional Chinese Medicine University Nanjing China |
| |
| Affiliation: | DING Yi jiang,HA Nan lin,DING Shu qing,XU Wen hua,GENG Jian xiang. Affiliated Nanjing Traditional Chinese Medicine Hospital,Nanjing Traditional Chinese Medicine University,Nanjing 210001,China |
| |
| Abstract: | |
| |
| Keywords: | Slow transit constipation Synapses Substance P Vasoactive intestinal polypeptide |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
