中西药联合治疗房颤复律后维持窦性心律的观察

目的观察厄贝沙坦、胺碘酮和稳心颗粒单用或联用在房颤复律后维持窦性心律的疗效.方法持续性房颤患者41例,恢复窦性心律后随机分为3组,分别用胺碘酮（A组,14例）、厄贝沙坦加胺碘酮（B组,15例）和稳心颗粒加厄贝沙坦加胺碘酮（C组,12例）治疗6个月.结果心脏彩超左房内径B组和C组治疗后均改善（P＜0.05）,且C组改善程度优于B组（P＜0.05）;左室舒张末期直径C组治疗后明显改善（P＜0.05）.窦性心律维持率C组高于A组（P＜0.05）.结论中西药联合应用有抗心律失常协同作用.

Effect of Combination of Chinese and Western Medicines on Sinus Rhythm Maintenance in Patients with Auricular Fibrillation after Conversion

Objective To investigate the curative effects of irbesartan, amiodar one and Wenxin Granule (WG), applied alone or in combination, on sinus rhythm m aintenance in patients with auricular fibrillation (AF) after conversion. Methods Forty-one patients of persistent AF, after their fibrillation being converted , were divided into three groups randomly, and treated with amiodarone (group A, n=14), irbesartan and amiodarone (group B, n=15), and WG plus irbesarta n and am iodarone (group C, n=12) respectively for 6 months. Results Compared with that before treatment, the inner diameter of atria sinistrum reduced in group B and C , and the reduction in the latter was superior to that in the former (P<0.05 ); t he diameter of left ventricle also reduced in group C (P<0.05); and the main tena nce rate of sinus rhythm was higher in group C than that in group A (P<0.05) . Conclusion Combined therapy of Chinese and Western medicines shows synergistic e ffect of anti-arrhythmia.