化疗并用卡提素治疗菌阳肺结核的疗效观察

目的 观察和评价化疗并用卡提素治疗菌阳肺结核的疗效。方法 将1998年新登记的200例初治、复治涂阳肺结核患者随机分为A、B、C、D组。A、C组（各50例）分别采用2H3R3Z3S3/4H3R3和2H3R3Z3E3S3/6H3R3E3并用卡提素方案治疗；B、D组（各50例）单纯用2H3R3Z3S3/4H3R3和2H3R3Z3S3/6H3R3E3方案治疗，观察治疗后痰菌阴转，病灶吸收，空沿改变及临床症状的消失情况。结果 第2月末痰菌阴转率；A、B组分别为100%和78%，C、D组分别为86%和66%；疗程结束痰菌阴转率；A、B组分别为100%和92%，C、D组分别为92%和66%；空洞吸收率；A、B、C、D组分别为80.0%,44.8%,72.5%，48.8%。结论 卡提素能提高痰菌阴转率，促进病灶吸收及空洞闭合，提高免疫细胞活性，是一种较好的免疫调节剂。

Observation on Curative Effect of Positive Bacteria Pulmonary Tuberculosis Treated by Chemotherapy and BCG- PSN

Objective To observe and evaluate the curative effect of positive bacteria pulmonary tuberculosis tueated by chemotherapy and BCG-PSN.Methods 200 primary and re-treated positive bacteria pulmonary tuberculosis of newly registered cases were separated into groups A?B?C?D by random.Grorp A(50 cases)and group C(50 cases)were treated by 2H_ 3 R_ 3 Z_ 3 S_ 3 /4H_ 3 R_ 3 and 2H_ 3 R_ 3 Z_ 3 E_ 3 S_ 3 /6H_ 3 R_ 3 E_ 3 with BCG-PSN .Group B(50 cases)and group D (50 cases)treated by 2H_ 3 R_ 3 Z_ 3 S_ 3 /4H_ 3 R_ 3 and 2H_ 3 R_ 3 Z_ 3 E_ 3 S_ 3 /6H_ 3 R_ 3 E_ 3 alone.Then the sputum negative conversion?the foci absorption?cavity closing up and symptom fleeing.were observed Results At the end of 2nd month,the sputum negative conversion rate to groups A?B?C?D was 100%,78%,86%and 66% respectly.At the end of treatment,the sputum negative conrersion rate to groups A?B?C?D was 100%,92%,96%and 76%;The foci absorption rate to groups A?B?C?D was 96%,84%,92%and 66% respectly.;cavity close up was 80%,44 8%,72 5%and 48 8% respectly.Conclusions BCG-PSN can improve the sputum negative conversion rate,accelerate the foci absorption and improve the vitality of immune cells.It is a better immunity injection.