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硝苯啶治疗重度高血压40例
引用本文:陈德源,雷玉艳,张华,柳丽莎,玛依热,庞玺惠. 硝苯啶治疗重度高血压40例[J]. 中国新药与临床杂志, 1990, 0(5)
作者姓名:陈德源  雷玉艳  张华  柳丽莎  玛依热  庞玺惠
作者单位:乌鲁木齐铁路局中心医院内科 乌鲁木齐830011(陈德源,雷玉艳,张华,柳丽莎,玛依热),乌鲁木齐铁路局鱼儿沟医院 830024(庞玺惠)
摘    要:以单剂硝苯啶10mg,舌下含用,治疗重度高血压(舒张压>15.3kPa)者40例,其中男21,女19;年龄61±SD6yr;病程17±6yr;用药后30min血压平均下降6.6/4.2kPa(P<0.01);心率增快10±5次/min;另外对30例患者用硝苯啶10-20mg,po,维持治疗共3mo;40例患者总有效率100%,显效率80%。不良反应轻微。

关 键 词:硝苯啶/治疗应用  高血压/药物疗法  心率

Treatment of advanced hypertension with nifedtpine in 40 patients
CHEN De-Yuan,LEI Yu-Yan,ZHANG Hua,LIU Li-Sha,MA Yi-Re,PANG Ki-Hui. Treatment of advanced hypertension with nifedtpine in 40 patients[J]. Chinese Journal of New Drugs and Clinical Remedies, 1990, 0(5)
Authors:CHEN De-Yuan  LEI Yu-Yan  ZHANG Hua  LIU Li-Sha  MA Yi-Re  PANG Ki-Hui
Affiliation:The Central Hospital of Urumqi Railway Bureau Uru7mqi 830011
Abstract:Forty patients(M21, F19;age 61+SD6yr) with advanced hyperten-sion were tteated withnifedipine 10 mg single dose sublingually and ambng them 30 patients then were followed with 10-20mg, tid, po for 3 mo. Thirty minutes after sublingual treatment, the lowering of blood pressure attained 6.6/4.2kPa(50/32 mmHg) P<0.01; heart rate was increased 10+5bpm (P<0.01).The total response rate was 100% and the marked effect was 80%. Adverse reactions were mild.
Keywords:nifedipine/therapeutic use  hypertension/drug therapy  heart fate  
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