| 石墨炉原子吸收法测定聚丙烯药用滴眼剂瓶铝元素迁移量 |
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| 引用本文： | 张广湘,雷秀峰. 石墨炉原子吸收法测定聚丙烯药用滴眼剂瓶铝元素迁移量[J]. 中国医药导报, 2010, 7(24): 43-44 |
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| 作者姓名： | 张广湘 雷秀峰 |
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| 作者单位： | 广东省医疗器械质量监督检验所药包材室,广东广州,510080 |
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| 摘 要： | 目的：建立石墨炉原子吸收法测定聚丙烯药用滴眼剂瓶铝元素迁移量,用以考察聚丙烯滴眼剂瓶的稳定性及安全性。方法：样品液直接用石墨炉原子吸收法测定。结果：标准曲线有较好的线性,相关系数为0.9964,加标回收率在93%～105%范围内。结论：本法重复性好、简便、迅速、可操作性强,可以作为评价聚丙烯滴眼剂瓶安全性的一项检测方法。
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| 关 键 词： | 石墨炉原子吸收 聚丙烯药用滴眼剂瓶 铝元素 迁移量 安全性 |
Determination of aluminum migrated from PP Bottle Eye Drops by. graphite furnace atomic absorption spectrometry |
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| ZHANG Guangxiang,LEI Xiufeng. Determination of aluminum migrated from PP Bottle Eye Drops by. graphite furnace atomic absorption spectrometry[J]. China Medical Herald, 2010, 7(24): 43-44 |
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| Authors: | ZHANG Guangxiang LEI Xiufeng |
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| Affiliation: | (Department of Pharmaceutical Packaging Material,Guangdong Medical Instruments Quality Surveillance and Inspection Institute,Guangzhou 510080,China) |
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| Abstract: | Objective：To establish a method for determination of aluminum migrated from PP Bottle Eye Drops by graphite furnace atomic absorption spectrometry,which can explore safety and stability of PP Bottle Eye Drops.Methods：Sample solutions were directly determined by graphite furnace atomic absorption spectrometry.Results：A good linearity was obtained（r=0.996 4）.The rates of recovery were between 93% and 105%.Conclusion：The method is easy and reliable to operate,which can apply exploration of safety of PP Bottle Eye Drops. |
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| Keywords: | Graphite furnace atomic absorption spectrometry PP Bottle Eye Drops Aluminum Migration Safety |
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