急性心肌梗死与高血糖

糖尿病是冠心病的独立危险因子。但非糖尿病急性心肌梗死患者亦常伴有血糖升高。有临床研究表明,非糖尿病急性心肌梗死患者早期血糖增高提示病情重、梗死面积大、并发症多、预后差及病死率高。血糖增高的程度与病情的严重程度密切相关。因此,提高对急性心肌梗死时血糖升高及其加重心肌损害和影响患者预后机制的认识,对伴有高血糖的急性心肌梗死患者进行积极的血糖控制,具有重要的意义。作者就血糖水平与无糖尿病急性心肌梗死患者预后的关系,以及加强对其进行血糖控制的研究进展作一综述。

Acute myocardial infarction and hyperglycemia

Diabetes mellitus is an independent risk factor for coronary artery disease,but patients without diabetes mellitus may also present hyperglycemia during acute myocardial infarction.Some clinical researches have manifested that higher blood glucose concentration in patients without diabetes mellitus during acute myocardial infarction indicates increased severity,larger size of infarction,more complications,worse prognosis and higher mortality.Thus,it is important to obtain a deeper understanding of the mechanism of hyperglycemia aggravating myocardial injury and influencing the prognosis during acute myocardial infarction and to control the blood glucose level in such patients.This article reviews the correlation between blood glucose concentration and the prognosis of acute myocardial infarction in patients without diabetes mellitus.