Devic's syndrome in systemic lupus erythematosus and probable antiphospholipid syndrome |
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Authors: | Ferreira S Marques P Carneiro E D'Cruz D Gama G |
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Affiliation: | Internal Medicine Department (B) and 1 Neuroradiology Department, São João Hospital, Porto, Portugal and 2 The Lupus Research Unit, The Rayne Institute, St Thomas' Hospital, London SE1 7EH, UK |
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Abstract: | Neuropsychiatric lupus is common and results in significantmorbidity [1, 2]. Antiphospholipid antibodies (aPL) may playa major role and are associated with transverse myelitis [24],often with a significant response to anticoagulation [4, 5].Devic's syndrome is described in multiple sclerosis (MS) [6]and has rarely been associated with systemic lupus erythematosus(SLE) [5, 79]. We present a 44-yr-old woman with SLEwho developed neuromyelitis optica and probable antiphospholipidsyndrome (APS). She was healthy until 1990 when schizophrenia was |
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