| RP-HPLC法测定利鼻片中黄芩苷的含量 |
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| 引用本文： | 徐冬,汪涛,张杰. RP-HPLC法测定利鼻片中黄芩苷的含量[J]. 中国药师, 2010, 13(2): 256-257 |
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| 作者姓名： | 徐冬 汪涛 张杰 |
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| 作者单位： | 浙江衢化医院药剂科,浙江衢州,324004 |
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| 摘 要： | 目的：建立RP—HPLC法测定利鼻片中黄芩苷含量的方法。方法：色谱柱：Phenomenex C18（250mm×4．6mm，5μm）；流动相：甲醇-水-磷酸（47：53：0．2）；检测波长：280nm；柱温：25oC；流速：1．0ml·min-1。结果：黄芩苷在0．019～0．757μg范围内呈良好的线性关系（r=1．0000），平均回收率为99．7％，RSD2．0％。结论：方法简便、快速、准确可靠，可作为该制剂的质控方法。
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| 关 键 词： | 高效液相色谱法 利鼻片 黄芩苷 |
Determination the Content of Baicalin in Libi Tablets by RP-HPLC |
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| Xu Dong,Wang Tao,Zhang Jie. Determination the Content of Baicalin in Libi Tablets by RP-HPLC[J]. China Pharmacist, 2010, 13(2): 256-257 |
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| Authors: | Xu Dong Wang Tao Zhang Jie |
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| Affiliation: | ( Department of Pharmacy, Quhua Hospital of Zhejiang Province, Zhejiang Quzhou 324004, China) |
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| Abstract: | Objective： To eatablish an HPLC method for determining the content of baicalin in libi tablets. Method ： Phenomenex Cls （250 mm ×4.6 mm,5 μm ） was used,methanol-water-phosphric acid （47： 53： 0. 2） was used as mobile phase;The detection wavelength was 280 nm and the flow rate was 1.0 ml.min-1. Result： Baicalin concentration presented a good linear range of 0. 019-0. 757 μg （r = 1. 000 0）, the average recovery was 99. 7% ,RSD = 2. 0%. Conclusion： The method is simple, rapid and accurate for the quality control of the preparation. |
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| Keywords: | HPLC Libi tablets Baicalin |
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