|
|||||
|
|
Effect of tremorine and oxotremorine on aerobic glycolysis in rat brain |
|
| Authors: | T Yoshida R Igi? |
| Institution: | Department of Pediatrics, Children Memorial Hospital and Department of Pharmacology, University of Oklahoma Health Sciences Centre, Oklahoma City, Oklahoma 73190, USA |
| Abstract: | Tremorine and oxotremorine at concentrations from 5 × 10?8 to 5 × 10?4 M stimulated aerobic glycolysis in slices of rat brain cortex. The addition of atropine blocked this stimulation. Acetylcholine in concentrations from 5 × 10?8 to 5 × 10?6 M failed to alter the rate of glycolysis in slices of cortex, but it inhibited glycolysis in concentrations of 5 × 10?5 and 5 × 10?4 M. In homogenates of rat brain cortex tremorine, oxotremorine and acetylcholine elicited no effect on aerobic glycolysis. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |